Mark Roth

Mark Roth

Senior Scientist, Translational Medicine

My focus at Fulcrum is Fragile X Syndrome on the Translational Medicine team.  My goal is to develop clinical biomarkers for a clinical trial.  I love to experimentally test new ideas and techniques and to problem solve. I’m here because I want a closer connection with the individuals Fulcrum intends to help.

I also love to go adventure seeking with my family.

Ning Shen

Ning Shen

Associate Scientist, Computational Biology

My focus is to study genomic regulation of disease genes using integrative computational approaches. I love the genomic aspects of biology and applying cutting edge computational methods to advance precision medicine. I am excited to be here because I believe in the power of computational biology and am honored to be contributing to efforts to help patients suffering from genetic diseases.

Outside of being a lifelong and avid animal lover, I have been spending much of my spare time getting to know Boston and Cambridge since my move from North Carolina!

Ling Lin

Ling Lin

Senior Scientist, Biology

My focus is target identification (product engine) on the Biology team. I love applying innovative technologies to investigate disease mechanisms and explore the potential modulation of disease causative genes. I also love integrating translational and clinical strategies in early stage drug discovery. I am here to discover transformative treatments for patients by targeting genetic causes of these challenging diseases.

When the weather permits, you can find me sailing in the Charles River and bird watching.

Sarah Coughlin

Sarah Coughlin

Human Resources/Office Operations

My focus at Fulcrum changes daily. I work with the entire team to accomplish whatever needs to be done.  
 
When I met Walt and Phil during my interview, their unwavering commitment to making an impact was palpable. They spoke of patients and families they knew by name. I knew I could not pass up THIS opportunity to be part of a team striving to transform the lives of patients and their families.
 
In addition to keeping the office running, you may also find me teaching yoga, paddleboarding, or showering my dog, Georgia, with love.

Steven Kazmirski

Steven Kazmirski

Director, Structural Biology and Biophysics

I focus on defining the molecular interactions of our small molecules with our target proteins.  I love seeing how the new compounds bind to their targets at the atomic level.  I am at Fulcrum as I find it the perfect opportunity to bring a novel therapy to untreated rare genetic diseases.

As an enthusiastic SCUBA diver, you can often find me exploring the world below water.

Alejandro Rojas

Alejandro Rojas

Senior Scientist, Biology

I joined the Biology team at Fulcrum to apply my passion for exploring new ways to unravel the molecular mechanisms behind gene regulation to the development of transformative medicines for patients and their families. I am thrilled at the opportunity to pursue this goal alongside our extremely talented and driven multidisciplinary team.

As an avid foodie, I also love exploring the food scenes in Boston and New York.