WE ARE RARE
Fulcrum is a great place to have a career. Why? Because we have the FULcrew! Our people make us great. At Fulcrum, you can count on finding coworkers who are passionate about their work. Our patient-centered, inclusive, and connected culture enables us to actively listen to the needs of the rare disease community as we lead our science. This makes us and our work rare!
OUR VALUES:
Voices of Fulcrum
An inside look at life, work, and purpose at Fulcrum.
Make your career a career with impact.
See our available roles below or connect with us at [email protected]
Stories from the FULcrew
Meet the FULcrew and hear our stories.
Are you looking for consistency, commitment, and passion in your career? Join us.
There is always hope for change when people are committed to moving forward together every day, without exception. We call this steadfast commitment our "20 Mile March," inspired by Jim Collins' book Good to Great. At Fulcrum, we pledge to show up passionately every day, dedicated to our work and each other, no matter the challenges we face.
Explore our job openings:
Over the past few months, we’ve been excited to welcome several new faces to the FULcrew. To all our new teammates - welcome! We’re thrilled to have you.
From patient to future physician, Hanif’s journey shows what hope and healing can look like for the sickle cell community.
#SickleCellAwareness #HarvardPreMed #StoriesOfStrength
Gathering for our All Hands just before Thanksgiving came with a meaningful reminder: none of this work happens alone.
We’re grateful for our team and for the rare disease community who continue to inspire, challenge, and partner with us.
Thank you for being part of this mission with us. Wishing you and your loved ones a warm and restful Thanksgiving!
#HappyThanksgiving #Biotech #RareDisease
Empowerment. Strength. Courage.
Those three words were more than a theme at SCDAA’s 53rd Annual Convention. They were the energy in every session, every conversation, and every moment.
Thank you to SCDAA for bringing the community together for this year’s convention, and to all the speakers who inspired us to keep forging ahead with strength and courage.
#SCDAA #Empowerment
We’re thrilled to welcome Lisa Percival as our new Chief Regulatory Officer!
With decades of global regulatory experience and a career dedicated to the development of new medicines for high unmet need diseases and expanding access for patients, Lisa brings exceptional leadership and expertise to the FULcrew.
Welcome to the team, Lisa!
#FULcrew #Leadership #Biotech #RareDisease
Today we honor those who’ve served. At Fulcrum, we also recognize that service can come with unseen challenges, including health risks linked to genetic traits like Sickle Cell Trait (SCT).
Service members with SCT face a 24% higher risk of complications during intense physical exertion. It’s a reminder of why lifelong, equitable healthcare for veterans matters and why awareness is key to protecting those who protect us.
Thank you to all who have served.
Source: Risk of Exertional Heat Illnesses Associated with Sickle Cell Trait in U.S. Military (2019)
#VeteransDay #SickleCellAwareness
This September, we honored Sickle Cell Awareness Month. It was a time to listen, learn, and take action alongside the people living this story every day.
Over the month, we had the chance to make fresh connections and reconnect in so many meaningful ways. From the Cayenne Wellness Summit to our Sickle Cell Warrior Panel, from community partnerships and walks in Houston and Michigan to our first global patient webinar, we were reminded that awareness is just the beginning.
Each moment and each person reminded us that what matters most are the connections that last long after September ends.
#SickleCellAwarenessMonth #SickleCellDisease #SickleCellCommunity
Happy Halloween! The FULcrew went all in on this year’s theme: “Dress like your job…but make it exaggerated!”
#DressLikeYourJob #CostumeChallenge
This week, our CEO, Alex Sapir, joined fellow leaders from the Rare Disease Company Coalition and the U.S. Food and Drug Administration (FDA), including Commissioner Dr. Martin Makary and CDER Director Dr. George Tidmarsh, at the RDCC–FDA CEO Roundtable on Rare Disease Drug Development.
Together, they explored ways to build on the FDA’s strong commitment to accelerate drug development for the rare disease community.
We’re grateful to be part of a community working together to turn research into real change for people living with rare diseases.
#RareDisease #TogetherForPatients
September marked Sickle Cell Awareness Month, and we came together for Stories of Strength in Sickle Cell Disease.
Thank you to Hanif Mouehla, Dr. Simone Eastman Uwan, Nola Juste, MPH, CCRP, and Derek Robertson, MBA, JD, CHC for sharing powerful perspectives as warriors, caregivers, and advocates.
Your voices remind us that change begins with listening and grows through action.
#SickleCellAwarenessMonth #AdvocacyInAction #CommunityVoices
Oktoberfest, Fulcrum-style! 🥨 Our team came together for a little Oktoberfest fun, complete with pretzels, beer sampling, and plenty of good cheer.
We were honored to sponsor & walk alongside the Massachusetts Sickle Cell Association at the 2025 Walk for Sickle Cell Disease in Franklin Park, Boston.
Together, we raise awareness, support families, and fight for a brighter future.
#WalkForSickleCell