WE ARE RARE

Fulcrum is a great place to have a career. Why? Because we have the FULcrew! Our people make us great. At Fulcrum, you can count on finding coworkers who are passionate about their work. Our patient-centered, inclusive, and connected culture enables us to actively listen to the needs of the rare disease community as we lead our science. This makes us and our work rare!

OUR VALUES:

Passionate.

We show up every day with commitment, purpose, and dedication to patients, the business, and each other.

Transformative.

We are scientific leaders focused on creating therapies that transform the lives of patients and caregivers.

Inclusive.

We have a welcoming culture that embraces and celebrates everyone, including the communities we serve.

Patient-Centered.

We actively listen to the needs of patients, caregivers, and our community as we lead our science. Patients and the advocacy community are the foundation of everything we do.

Connected.

We invest in our people so we can learn, innovate, and grow together. Empowerment and camaraderie are pivotal to our progress.

Voices of Fulcrum

An inside look at life, work, and purpose at Fulcrum.

Make your career a career with impact.

See our available roles below or connect with us at [email protected]

Stories from the FULcrew

Meet the FULcrew and hear our stories.

Explore our job openings:

From patient to future physician, Hanif’s journey shows what hope and healing can look like for the sickle cell community.

#SickleCellAwareness #HarvardPreMed #StoriesOfStrength
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Gathering for our All Hands just before Thanksgiving came with a meaningful reminder: none of this work happens alone.

We’re grateful for our team and for the rare disease community who continue to inspire, challenge, and partner with us.

Thank you for being part of this mission with us. Wishing you and your loved ones a warm and restful Thanksgiving!

#HappyThanksgiving #Biotech #RareDisease
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We’re thrilled to welcome Lisa Percival as our new Chief Regulatory Officer!

With decades of global regulatory experience and a career dedicated to the development of new medicines for high unmet need diseases and expanding access for patients, Lisa brings exceptional leadership and expertise to the FULcrew.

Welcome to the team, Lisa!

#FULcrew #Leadership #Biotech #RareDisease
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Today we honor those who’ve served. At Fulcrum, we also recognize that service can come with unseen challenges, including health risks linked to genetic traits like Sickle Cell Trait (SCT).

Service members with SCT face a 24% higher risk of complications during intense physical exertion. It’s a reminder of why lifelong, equitable healthcare for veterans matters and why awareness is key to protecting those who protect us.

Thank you to all who have served.

Source: Risk of Exertional Heat Illnesses Associated with Sickle Cell Trait in U.S. Military (2019)

#VeteransDay #SickleCellAwareness
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This week, our CEO, Alex Sapir, joined fellow leaders from the Rare Disease Company Coalition and the U.S. Food and Drug Administration (FDA), including Commissioner Dr. Martin Makary and CDER Director Dr. George Tidmarsh, at the RDCC–FDA CEO Roundtable on Rare Disease Drug Development.

Together, they explored ways to build on the FDA’s strong commitment to accelerate drug development for the rare disease community.

We’re grateful to be part of a community working together to turn research into real change for people living with rare diseases.

#RareDisease #TogetherForPatients
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