About

Our Story

We launched Fulcrum Therapeutics with a bold vision: To change the course of genetically defined diseases by treating them at their root cause.

Our approach to drug discovery generates significant insights into disease biology and allows us to think creatively about the best way to modulate and balance gene expression. The result: A patient-focused product engine designed to systematically identify and validate cellular drug targets that can modulate gene expression to treat the known root cause of genetically defined diseases.

We take great pride in being purposeful patient partners who do this work, not just for patients, but with patients. We have a culture of trust and transparency which enables our employees to focus on our mission and the science behind it. In addition, we are invested in our people and want to ensure they have the tools and training they need to succeed. This allows our playful spirit to come alive, making work more enjoyable for our entire Fulcrew.

Robert J. Gould

Robert J. Gould

President and Chief Executive Officer, Board Member
Robert J. Gould
President and Chief Executive Officer, Board Member
Robert J. Gould joined Fulcrum as president and CEO at the time of the company’s launch in 2016, bringing over 30 years of experience to the role. Previously, he served as president and CEO of Epizyme from 2010 to 2015. Prior to joining Epizyme, Robert served as director of novel therapeutics at Broad Institute of MIT and Harvard from 2006 to 2010. Robert spent 23 years at Merck where he held a variety of leadership positions, culminating in the role of vice president, licensing and external research. During his time at Merck, Robert was instrumental in advancing more than 20 compounds from discovery into clinical development in multiple therapeutic areas. Robert received a bachelor’s from Spring Arbor University and a Ph.D. from the University of Iowa and completed postdoctoral studies at Johns Hopkins University.
Owen Wallace

Owen Wallace

Chief Scientific Officer
Owen Wallace
Chief Operating Officer
Owen Wallace joined Fulcrum in April 2017. He has more than two decades of experience in drug discovery and development across multiple therapeutic areas, including neuroscience, endocrine, infectious, respiratory and rare diseases. He is the co-inventor of seven clinical candidates and has overseen teams who have progressed more than 30 compounds into clinical development. Prior to joining Fulcrum, Owen served as head, global discovery chemistry at Novartis, where he was responsible for teams and projects across multiple sites in several disease areas and the chemical genetics field. Prior to Novartis, he was the site scientific leader with Eli Lilly & Company in the United Kingdom, leading a cross-functional team focusing on Alzheimer’s disease and schizophrenia. Before that, he held research positions at Bristol-Myers Squibb, where he co-initiated a program on a novel mechanism for inhibiting HIV infection that is now in Phase 3 clinical trials. Owen earned his Ph.D. in organic chemistry from Yale University.

Bryan Stuart

Bryan Stuart

Chief Operating Officer
Bryan Stuart
Chief Operating Officer
Bryan Stuart joined Fulcrum as chief operating officer in 2018, bringing over 20 years of experience building biopharmaceutical companies, including deal-making, capital raising and strategic and operational leadership. Most recently, he was the president and CEO of Yarra Therapeutics, a subsidiary of Array BioPharma focused on genetically defined rare diseases. Previously, Bryan served as president, then CEO of Kastle Therapeutics, a biopharmaceutical company focused on developing and commercializing therapeutics for rare diseases. Prior to Kastle, Bryan was the chief business officer of Civitas Therapeutics, where he led the business development, capital raising, commercial and portfolio management functions, including the planned IPO and company sale to Acorda (acquired Civitas day of scheduled IPO pricing). He previously led business development, corporate development and strategy at both EKR Therapeutics (acquired by Chiesi) and Ovation Pharmaceuticals (acquired by Lundbeck A/S), where he played key roles in each company’s growth and led the successful sale of both companies. Bryan began his career as a healthcare investment banker at William Blair & Company. He has an MBA from the Kellogg School at Northwestern University and a bachelor’s from the University of Illinois.

Kim Hazen

Kim Hazen

Senior Vice President, Human Resources
Kim Hazen
Vice President, Human Resources
Kim Hazen joined Fulcrum in September 2017 with over 25 years of experience in human resources. Most recently, she was vice president of human resources at Warp Drive Bio, where she led efforts to build a drug discovery culture and core values to match with an emphasis on elite performance. Prior to joining Fulcrum and Warp Drive Bio, Kim served as the executive director of human resources at Aegerion Pharmaceuticals and as head of human resources at the Broad Institute of MIT and Harvard. Before joining the life sciences industry, she worked on the investment side of human resources at Pioneer Investments, Fidelity Investments, Liberty Mutual and Bank of America. Kim received a bachelor’s in psychology from SUNY Potsdam and her MBA from Boston University.

Pamela Strode

Pamela Strode

Senior Vice President, Regulatory Affairs and Quality Assurance
Pamela S. Strode
Senior Vice President, Regulatory Affairs and Quality Assurance
Pamela (Pam) Strode joined Fulcrum in September 2019. She comes to Fulcrum from Epizyme, where she served as senior vice president, regulatory affairs and quality assurance, and played a critical role in establishing the team’s regulatory affairs and quality assurance departments. At Epizyme, Pam directed multiple U.S. Fast Track and U.S./E.U. Orphan Drug Designations and also led the regulatory strategy and operations for several clinical trial applications and a New Drug Application (NDA). She brings more than 30 years of regulatory leadership for investigational and marketed products across multiple therapeutic areas, with increasing levels of responsibility at Bristol-Myers Squibb, Boehringer Ingelheim Pharmaceuticals, Inc. and Cerulean Pharma. Pam has a B.S. in microbiology from Cook College at Rutgers University and an M.S. in QA/RA from Temple University, where she also obtained a Drug Development Certificate.

Peter Thomson

Peter Thomson

Vice President, Finance and Accounting
Peter Thomson
Vice President, Finance and Accounting
Peter Thomson joined Fulcrum in 2018, bringing over 15 years of experience in the life sciences industry. Most recently, he was a consultant for three Third Rock Ventures portfolio companies, where he served as interim head of finance. Before that, he served as head of finance at BIND Therapeutics, where he oversaw all finance and accounting activities, developed the corporate valuation for the company and played an integral role in the company’s sale to Pfizer. Prior to BIND, he was senior director of finance at Ovascience and director of finance at Millennium: The Takeda Oncology Company. In addition, he held positions on the finance teams at Boston Scientific Corporation, Infomedics, Inc., and the Hewlett-Packard Company. Peter earned a bachelor’s from Brown University and an MBA from the University of Chicago Booth School of Business.
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Nicole T. Gallagher

Nicole T. Gallagher

Senior Manager, Administrative Services
Nicole Gallagher
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Nicole Gallagher has been an Executive Administrative Assistant to the CEO and President and Manager of Administrative Services at Fulcrum Therapeutics since April 2017. Prior to joining Fulcrum, Nicole’s 18-year career has included roles in Administration at Abcam, Tapestry Networks, Aviva Life Insurance and Enterprise Rent-A-Car.

In her role at Fulcrum she has earned the trust and respect of her colleagues and has worked to develop close bonds and strong working relationships with a range of stakeholders, including patient communities and vendors. In her role as head of administrative services she is the primary Fulcrum contact for many vendors, manages needs related to the board of directors and supports internal and external communications strategies. She drives many efforts designed to maintain a positive and welcoming culture of teamwork and collaboration at Fulcrum. She is especially dedicated to inspiring team members with the stories of patients, saying, “To see and hear from them tells us what we’re working towards and makes it more real.”

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Curtis Oltmans

Curtis Oltmans

General Counsel

Curtis Oltmans joined Fulcrum as General Counsel in November 2020 with over 25 years of experience in
corporate law including senior management positions in legal departments at several leading
pharmaceutical and biotechnology companies. He most recently served as Vice President, Head of
Litigation at DaVita Kidney Care, Inc. where he led a 30-person team and was responsible for all
litigation, workers’ compensation and employee safety matters. Prior to DaVita, Curtis was Executive
Vice President, General Counsel and Corporate Secretary at Array BioPharma Inc. where he oversaw all
legal, corporate governance, patent and compliance matters. He previously served as Corporate Vice
President and General Counsel for Novo Nordisk, Inc., North America where he was responsible for
strategic support in areas including market access, government affairs, communications and product
marketing. He has also served as Assistant General Counsel for Eli Lilly and Company after beginning his
legal career supporting clients in pharmaceutical and medical device litigation matters. Curtis received a
BA in political science from the University of Nebraska and his JD from the University of Nebraska
College of Law.